BioDlink, a leading global CDMO, extends its congratulations to Junshi Biosciences (HKEX-1877; SSE-688180), on receiving Investigational New Drug (IND) approval from China’s National Medical Products Administration (NMPA) for JS212, a bispecific antibody-drug conjugate (ADC) designed to target both EGFR and HER3 receptors. JS212 represents a new class of bispecific ADCs that combine the humanized epidermal growth factor receptor and human epidermal growth factor receptor 3 bispecific antibody-drug conjugate to target both EGFR and HER3 — two proteins highly expressed in a variety of tumor cells, such as lung cancer, breast cancer, and head and neck cancer. As a bispecific ADC, JS212…

New national data reveal a sharp rise in GLP-1 prescriptions for young women, but low contraception use leaves many at risk of unintended pregnancy and uncertain outcomes for their babies. Study: Incidence of GLP-1 receptor agonist use by women of reproductive age attending general practices in Australia, 2011–2022: a retrospective open cohort study. Image credit: Tetiana_Kryvous/Shutterstock.com A new study in the Medical Journal of Australia examines the use of glucagon-like peptide 1 (GLP-1) receptor agonists (RAs) in reproductive-age women in Australia to effectively manage type 2 diabetes mellitus, along with contraception overlap and pregnancy incidence in this population. Introduction GLP-1…

Infamous for their environmental persistence and potential links to health conditions, per- and polyfluoroalkyl substances (PFAS), often called forever chemicals, are being discovered in unexpected places, including beer. Researchers publishing in ACS’ Environmental Science & Technology tested beers brewed in different areas around the U.S. for these substances. They found that beers produced in parts of the country with known PFAS-contaminated water sources showed the highest levels of forever chemicals. “As an occasional beer drinker myself, I wondered whether PFAS in water supplies was making its way into our pints,” says research lead Jennifer Hoponick Redmon. “I hope these findings…

Charlie Kirk was shot and killed at an event at Utah Valley University. The incident has sparked nationwide condemnation and raised concerns about political violence. Security measures for controversial speakers are under scrutiny. Political leaders and the FBI are actively responding to the shooting. Kirk’s death has touched a chord internationally, with vigils and tributes planned. On Wednesday, September 10, 2025, conservative activist and Turning Point USA co-founder Charlie Kirk was shot and killed at an event at Utah Valley University. The incident, which occurred during an outdoor debate, has sent shockwaves through the…

Hormones like estrogen may help with gastrointestinal (GI) inflammation and the gut microbiome, so their decline may prompt more severe Crohn’s symptoms. [7] [8]  “[But] studies on the relationship between menopause and inflammatory bowel disease (IBD) have shown mixed, inconclusive results,” says Adalberto Gonzalez, MD, a gastroenterologist with Cleveland Clinic in Florida. [9] “On the one hand, women with Crohn’s disease whose symptoms worsened with fluctuating estrogen levels during their menstrual cycles may find relief after menopause because of an overall decrease in estrogen levels,” says Dr. Gonzalez. On the other hand, decreased levels of estrogen and progesterone from menopause…

You may already be using the over-the-counter nasal spray azelastine (Astepro) to relieve allergy symptoms, like sneezing, a stuffy nose, and watery eyes. [1] A new clinical trial suggests this antihistamine may also help prevent COVID-19. [2] The study, published in JAMA Internal Medicine, found that the incidence of COVID-19 was significantly lower with application of azelastine nasal spray compared with a placebo treatment, says study author Peter Meiser, PhD, a representative of the pharmaceutical company and study sponsor Ursapharm Arzneimittel in Saarbruecken, Germany. “We consider azelastine nasal spray, based on its established safety profile, over-the-counter availability, and ease of…